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Structural Advances in Voltage-Gated Sodium Channels

Voltage-gated sodium (Na(V)) channels are responsible for the rapid rising-phase of action potentials in excitable cells. Over 1,000 mutations in Na(V) channels are associated with human diseases including epilepsy, periodic paralysis, arrhythmias and pain disorders. Natural toxins and clinically-us...

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Detalles Bibliográficos
Autores principales: Jiang, Daohua, Zhang, Jiangtao, Xia, Zhanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204039/
https://www.ncbi.nlm.nih.gov/pubmed/35721169
http://dx.doi.org/10.3389/fphar.2022.908867