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Epigenetic Clocks for Mice Based on Age-Associated Regions That are Conserved Between Mouse Strains and Human

Aging of mice can be tracked by DNA methylation changes at specific sites in the genome. In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated D...

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Detalles Bibliográficos
Autores principales: Perez-Correa, Juan-Felipe, Tharmapalan, Vithurithra, Geiger, Hartmut, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204067/
https://www.ncbi.nlm.nih.gov/pubmed/35721486
http://dx.doi.org/10.3389/fcell.2022.902857