12-Deoxyphorbol-13-Hexadecanoate Abrogates OVX-Induced Bone Loss in Mice and Osteoclastogenesis via Inhibiting ROS Level and Regulating RANKL-Mediated NFATc1 Activation

Osteoporosis is a major health problem in the elderly. Almost every bone can fracture due to the increased bone fragility in osteoporosis, posing a major challenge to public health. 12-Deoxyphorbol-13-hexadecanoate (DHD), one of the main bioactive components of Stellera chamaejasme L. (Lang Du), is...

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Detalles Bibliográficos
Autores principales: He, Qi, Yang, Junzheng, Chen, Delong, Li, Yejia, Gong, Dawei, Ge, Hui, Wang, Zihao, Wang, Haibin, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204068/
https://www.ncbi.nlm.nih.gov/pubmed/35721216
http://dx.doi.org/10.3389/fphar.2022.899776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204068/
https://www.ncbi.nlm.nih.gov/pubmed/35721216
http://dx.doi.org/10.3389/fphar.2022.899776

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