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12-Deoxyphorbol-13-Hexadecanoate Abrogates OVX-Induced Bone Loss in Mice and Osteoclastogenesis via Inhibiting ROS Level and Regulating RANKL-Mediated NFATc1 Activation

Osteoporosis is a major health problem in the elderly. Almost every bone can fracture due to the increased bone fragility in osteoporosis, posing a major challenge to public health. 12-Deoxyphorbol-13-hexadecanoate (DHD), one of the main bioactive components of Stellera chamaejasme L. (Lang Du), is...

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Detalles Bibliográficos
Autores principales:	He, Qi, Yang, Junzheng, Chen, Delong, Li, Yejia, Gong, Dawei, Ge, Hui, Wang, Zihao, Wang, Haibin, Chen, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204068/ https://www.ncbi.nlm.nih.gov/pubmed/35721216 http://dx.doi.org/10.3389/fphar.2022.899776

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