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Pimobendan Inhibits HBV Transcription and Replication by Suppressing HBV Promoters Activity

Current anti-HBV therapeutic strategy relies on interferon and nucleos(t)ide-type drugs with the limitation of functional cure, inducing hepatitis B surface antigen (HBsAg) loss in very few patients. Notably, the level of HBsAg has been established as an accurate indicator to evaluate the drug effic...

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Detalles Bibliográficos
Autores principales: Yuan, Si-Yu, Yu, Hai-Bo, Yang, Zhen, Qin, Yi-Ping, Ren, Ji-Hua, Cheng, Sheng-Tao, Ren, Fang, Law, Betty Yuen Kwan, Wong, Vincent Kam Wai, Ng, Jerome P. L., Zhou, Yu-Jiao, He, Xin, Tan, Ming, Zhang, Zhen-Zhen, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204083/
https://www.ncbi.nlm.nih.gov/pubmed/35721154
http://dx.doi.org/10.3389/fphar.2022.837115