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Engineering of Src Homology 2 Domain Leading to Sulfotyrosine Recognition With a High Affinity by Integrating a Distinctive Selection Theme and Next-Generation Sequencing

Tyrosine sulfation plays a vital role in various biochemical reactions. Although sulfated tyrosine (sTyr) has a similar structure to phosphotyrosine (pTyr), the number of available sTyr sites is significantly less than that of pTyr sites, mainly because of the lack of effective sTyr probes. A few sT...

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Detalles Bibliográficos
Autores principales: Zhao, Dongping, Li, Chan, Jiang, Haoqiang, Yin, Yuqing, Zhou, Changjing, Huang, Haiming, Qi, Yunkun, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204161/
https://www.ncbi.nlm.nih.gov/pubmed/35722314
http://dx.doi.org/10.3389/fmicb.2022.901558