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Type 2 and Type 17 Invariant Natural Killer T Cells Contribute to Local Eosinophilic and Neutrophilic Inflammation and Their Function Is Regulated by Mucosal Microenvironment in Nasal Polyps

Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by heterogeneous inflammatory endotypes of unknown etiology. Invariant natural killer T (iNKT) cells are multifunctional innate T cells that exhibit Th1-, Th2-, and Th17-like characteristics. We investigated functional relationships...

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Detalles Bibliográficos
Autores principales: Ye, Xiaoyan, Bao, Qing, Chen, Hexin, Meng, Qingxiang, Li, Qianying, Sun, Lin, Li, Jian, Lei, Wenbin, Wen, Weiping, He, Wenjing, Jiao, Linyi, Fang, Bixing, Gao, Yifang, Li, Chunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204195/
https://www.ncbi.nlm.nih.gov/pubmed/35720287
http://dx.doi.org/10.3389/fimmu.2022.803097