Pyridoxamine and Aminoguanidine Attenuate the Abnormal Aggregation of β-Tubulin and Suppression of Neurite Outgrowth by Glyceraldehyde-Derived Toxic Advanced Glycation End-Products

Diabetes mellitus (DM) has been identified as a risk factor for the onset and progression of Alzheimer’s disease (AD). In our previous study, we demonstrated that glyceraldehyde (GA)-derived toxic advanced glycation end-products (toxic AGEs, TAGE) induced similar alterations to those observed in AD....

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Detalles Bibliográficos
Autores principales: Ooi, Hayahide, Nasu, Ryuto, Furukawa, Ayako, Takeuchi, Masayoshi, Koriyama, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204210/
https://www.ncbi.nlm.nih.gov/pubmed/35721214
http://dx.doi.org/10.3389/fphar.2022.921611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204210/
https://www.ncbi.nlm.nih.gov/pubmed/35721214
http://dx.doi.org/10.3389/fphar.2022.921611

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