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AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver

The aryl hydrocarbon receptor (AhR) is a ubiquitously expressed ligand-activated transcription factor. While initially identified as an environmental sensor, this receptor has been shown more recently to regulate a variety of immune functions. AhR ligands vary in structure and source from environmen...

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Detalles Bibliográficos
Autores principales: Cannon, Alkeiver S., Holloman, Bryan Latrell, Wilson, Kiesha, Miranda, Kathryn, Dopkins, Nicholas, Nagarkatti, Prakash, Nagarkatti, Mitzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204231/
https://www.ncbi.nlm.nih.gov/pubmed/35720411
http://dx.doi.org/10.3389/fimmu.2022.899609