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Targeted Screening for Alzheimer's Disease Clinical Trials Using Data-Driven Disease Progression Models
Heterogeneity in Alzheimer's disease progression contributes to the ongoing failure to demonstrate efficacy of putative disease-modifying therapeutics that have been trialed over the past two decades. Any treatment effect present in a subgroup of trial participants (responders) can be diluted b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204250/ https://www.ncbi.nlm.nih.gov/pubmed/35719690 http://dx.doi.org/10.3389/frai.2022.660581 |