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Absence of P2Y(2) Receptor Does Not Prevent Bone Destruction in a Murine Model of Muscle Paralysis-Induced Bone Loss

Increased incidence of bone fractures in the elderly is associated with gradual sarcopenia. Similar deterioration of bone quality is seen with prolonged bed rest, spinal cord injuries or in astronauts exposed to microgravity and, preceded by loss of muscle mass. Signaling mechanisms involving uridin...

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Detalles Bibliográficos
Autores principales: Agrawal, Ankita, Ellegaard, Maria, Haanes, Kristian Agmund, Wang, Ning, Gartland, Alison, Ding, Ming, Praetorius, Helle, Jørgensen, Niklas Rye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204296/
https://www.ncbi.nlm.nih.gov/pubmed/35721713
http://dx.doi.org/10.3389/fendo.2022.850525