Cargando…

SQLE, A Key Enzyme in Cholesterol Metabolism, Correlates With Tumor Immune Infiltration and Immunotherapy Outcome of Pancreatic Adenocarcinoma

BACKGROUND: Pancreatic adenocarcinoma (PAAD) is a treatment-refractory cancer with poor prognosis. Accumulating evidence suggests that squalene epoxidase (SQLE) plays a pivotal role in the development and progression of several cancer types in humans. However, the function and underlying mechanism o...

Descripción completa

Detalles Bibliográficos
Autores principales: You, Weiqiang, Ke, Jia, Chen, Yufeng, Cai, Zerong, Huang, Ze-ping, Hu, Peishan, Wu, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204319/
https://www.ncbi.nlm.nih.gov/pubmed/35720314
http://dx.doi.org/10.3389/fimmu.2022.864244