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Fasciola hepatica Fatty Acid Binding Protein 1 Modulates T cell Polarization by Promoting Dendritic Cell Thrombospondin-1 Secretion Without Affecting Metabolic Homeostasis in Obese Mice

BACKGROUND: The parasitic trematode Fasciola hepatica evades host immune defenses through secretion of various immunomodulatory molecules. Fatty Acid Binding Proteins (fhFABPs) are among the main excreted/secreted proteins and have been shown to display anti-inflammatory properties. However, little...

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Detalles Bibliográficos
Autores principales: Zawistowska-Deniziak, Anna, Lambooij, Joost M., Kalinowska, Alicja, Patente, Thiago A., Łapiński, Maciej, van der Zande, Hendrik J. P., Basałaj, Katarzyna, de Korne, Clarize M., Chayé, Mathilde A. M., Gasan, Thomas A., Norbury, Luke J., Giera, Martin, Zaldumbide, Arnaud, Smits, Hermelijn H., Guigas, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204345/
https://www.ncbi.nlm.nih.gov/pubmed/35720355
http://dx.doi.org/10.3389/fimmu.2022.884663