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A Global Regulatory Network for Dysregulated Gene Expression and Abnormal Metabolic Signaling in Immune Cells in the Microenvironment of Graves’ Disease and Hashimoto’s Thyroiditis

BACKGROUND: Although the pathogenetic mechanisms of Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) have been elucidated, the molecular mechanisms by which the abnormal immune function of cellular subpopulations trigger an autoimmune attack on thyroid tissue largely remains unexplained. METHOD...

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Detalles Bibliográficos
Autores principales: Zheng, Haitao, Xu, Jie, Chu, Yongli, Jiang, Wenzhou, Yao, Wenjie, Mo, Shaowen, Song, Xicheng, Zhou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204353/
https://www.ncbi.nlm.nih.gov/pubmed/35720300
http://dx.doi.org/10.3389/fimmu.2022.879824