Wilms tumor reveals DNA repair gene hyperexpression is linked to lack of tumor immune infiltration

BACKGROUND: A T cell-rich tumor microenvironment has been associated with improved clinical outcome and response to immune checkpoint blockade therapies in several adult cancers. Understanding the mechanisms for lack of immune cell infiltration in tumors is critical for expanding immunotherapy effic...

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Detalles Bibliográficos
Autores principales: Higgs, Emily F, Bao, Riyue, Hatogai, Ken, Gajewski, Thomas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204399/
https://www.ncbi.nlm.nih.gov/pubmed/35705315
http://dx.doi.org/10.1136/jitc-2022-004797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204399/
https://www.ncbi.nlm.nih.gov/pubmed/35705315
http://dx.doi.org/10.1136/jitc-2022-004797

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