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A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins
E3 ligases constitute a large and diverse family of proteins that play a central role in regulating protein homeostasis by recruiting substrate proteins via recruitment domains to the proteasomal degradation machinery. Small molecules can either inhibit, modulate or hijack E3 function. The latter cl...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204419/ https://www.ncbi.nlm.nih.gov/pubmed/35721509 http://dx.doi.org/10.3389/fcell.2022.886537 |