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A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins

E3 ligases constitute a large and diverse family of proteins that play a central role in regulating protein homeostasis by recruiting substrate proteins via recruitment domains to the proteasomal degradation machinery. Small molecules can either inhibit, modulate or hijack E3 function. The latter cl...

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Detalles Bibliográficos
Autores principales: Schwalm, Martin P., Berger, Lena M., Meuter, Maximilian N., Vasta, James D., Corona, Cesear R., Röhm, Sandra, Berger, Benedict-Tilman, Farges, Frederic, Beinert, Sebastian M., Preuss, Franziska, Morasch, Viktoria, Rogov, Vladimir V., Mathea, Sebastian, Saxena, Krishna, Robers, Matthew B., Müller, Susanne, Knapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204419/
https://www.ncbi.nlm.nih.gov/pubmed/35721509
http://dx.doi.org/10.3389/fcell.2022.886537