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Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

Hematopoietic stem cells (HSCs) regenerate blood cells upon hematopoietic injuries. During homeostasis, HSCs are maintained in a low reactive oxygen species (ROS) state to prevent exhaustion. However, the role of nitric oxide (NO) in controlling HSC regeneration is still unclear. Here, we find incre...

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Detalles Bibliográficos
Autores principales: Yi, Weiwei, Zhang, Yuying, Liu, Bo, Zhou, Yuanyuan, Liao, Dandan, Qiao, Xinhua, Gao, Dan, Xie, Ting, Yao, Qin, Zhang, Yao, Qiu, Yugang, Huang, Gang, Chen, Zhiyang, Chen, Chang, Ju, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204508/
https://www.ncbi.nlm.nih.gov/pubmed/33789111
http://dx.doi.org/10.1016/j.celrep.2021.108922