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Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice

Activation of the renin–angiotensin system has been implicated in hypertension. Angiotensin (Ang) II is a potent proinflammatory mediator. The present study investigated the role of myeloid angiotensin type 1 receptor (AT1R) in control of macrophage phenotype in vitro and vascular injury in deoxycor...

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Detalles Bibliográficos
Autores principales: Yang, Xue-Feng, Wang, Huan, Huang, Yue, Huang, Jian-Hua, Ren, Hao-Lin, Xu, Qian, Su, Xiao-Min, Wang, Ai-Mei, Ren, Fu, Zhou, Ming-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204513/
https://www.ncbi.nlm.nih.gov/pubmed/35721173
http://dx.doi.org/10.3389/fphar.2022.879693