Targeting PCSK9 Ameliorates Graft Vascular Disease in Mice by Inhibiting NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells

BACKGROUND: Graft vascular disease (GVD), which limits the long-term survival of patients after solid-organ transplantation, is associated with both immune responses and nonimmune factors, including dyslipidemia. Recent studies have shown that inhibition of proprotein convertase subtilisin/kexin typ...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Yanqiang, Chen, Zhang, Zhang, Xi, Yu, Jizhang, Xu, Heng, Cui, Jikai, Li, Yuan, Niu, Yuqing, Zhou, Cheng, Xia, Jiahong, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204514/
https://www.ncbi.nlm.nih.gov/pubmed/35720337
http://dx.doi.org/10.3389/fimmu.2022.894789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204514/
https://www.ncbi.nlm.nih.gov/pubmed/35720337
http://dx.doi.org/10.3389/fimmu.2022.894789

Ejemplares similares