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Targeting PCSK9 Ameliorates Graft Vascular Disease in Mice by Inhibiting NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells

BACKGROUND: Graft vascular disease (GVD), which limits the long-term survival of patients after solid-organ transplantation, is associated with both immune responses and nonimmune factors, including dyslipidemia. Recent studies have shown that inhibition of proprotein convertase subtilisin/kexin typ...

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Detalles Bibliográficos
Autores principales:	Zou, Yanqiang, Chen, Zhang, Zhang, Xi, Yu, Jizhang, Xu, Heng, Cui, Jikai, Li, Yuan, Niu, Yuqing, Zhou, Cheng, Xia, Jiahong, Wu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204514/ https://www.ncbi.nlm.nih.gov/pubmed/35720337 http://dx.doi.org/10.3389/fimmu.2022.894789

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