Novel Stilbene-Nitroxyl Hybrid Compounds Display Discrete Modulation of Amyloid Beta Toxicity and Structure

Several neurodegenerative diseases are driven by misfolded proteins that assemble into soluble aggregates. These “toxic oligomers” have been associated with a plethora of cellular dysfunction and dysregulation, however the structural features underlying their toxicity are poorly understood. A major...

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Detalles Bibliográficos
Autores principales: Hilt, Silvia, Liu, Ruiwu, Maezawa, Izumi, Rojalin, Tatu, Aung, Hnin H., Budamagunta, Madhu, Slez, Ryan, Gong, Qizhi, Carney, Randy P., Voss, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204515/
https://www.ncbi.nlm.nih.gov/pubmed/35720993
http://dx.doi.org/10.3389/fchem.2022.896386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204515/
https://www.ncbi.nlm.nih.gov/pubmed/35720993
http://dx.doi.org/10.3389/fchem.2022.896386

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