Intestine-Specific NHE3 Deletion in Adulthood Causes Microbial Dysbiosis

In the intestine, the Na(+)/H(+) exchanger 3 (NHE3) plays a critical role for Na(+) and fluid absorption. NHE3 deficiency predisposes patients to inflammatory bowel disease (IBD). In mice, selective deletion of intestinal NHE3 causes various local and systemic pathologies due to dramatic changes in...

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Detalles Bibliográficos
Autores principales: Xue, Jianxiang, Dominguez Rieg, Jessica A., Thomas, Linto, White, James R., Rieg, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204535/
https://www.ncbi.nlm.nih.gov/pubmed/35719363
http://dx.doi.org/10.3389/fcimb.2022.896309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204535/
https://www.ncbi.nlm.nih.gov/pubmed/35719363
http://dx.doi.org/10.3389/fcimb.2022.896309

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