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Intestine-Specific NHE3 Deletion in Adulthood Causes Microbial Dysbiosis
In the intestine, the Na(+)/H(+) exchanger 3 (NHE3) plays a critical role for Na(+) and fluid absorption. NHE3 deficiency predisposes patients to inflammatory bowel disease (IBD). In mice, selective deletion of intestinal NHE3 causes various local and systemic pathologies due to dramatic changes in...
Autores principales: | Xue, Jianxiang, Dominguez Rieg, Jessica A., Thomas, Linto, White, James R., Rieg, Timo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204535/ https://www.ncbi.nlm.nih.gov/pubmed/35719363 http://dx.doi.org/10.3389/fcimb.2022.896309 |
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