Germacrone induces caspase-3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis

Liver cancer is a highly lethal malignancy. Despite considerable efforts made in recent years, the prognosis of patients with liver cancer remains poor. Curcuma zedoaria (known as Ezhu in Chinese) is widely prescribed in traditional Chinese medicine. Germacrone (GM) is a sesquiterpene constituent de...

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Detalles Bibliográficos
Autores principales: Sun, Xinfeng, Zhong, Xin, Ma, Wenfeng, Feng, Wenxing, Huang, Qi, Ma, Mengqing, Lv, Minling, Hu, Rui, Han, Zhiyi, Li, Jing, Zhou, Xiaozhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204551/
https://www.ncbi.nlm.nih.gov/pubmed/35747157
http://dx.doi.org/10.3892/etm.2022.11383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204551/
https://www.ncbi.nlm.nih.gov/pubmed/35747157
http://dx.doi.org/10.3892/etm.2022.11383

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