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Journey on the Radical SAM Road as an Accidental Pilgrim
[Image: see text] Radical S-adenosyl-l-methionine (SAM) enzymes catalyze a diverse group of complex transformations in all aspects of cellular physiology. These metalloenzymes bind SAM to a 4Fe–4S cluster and reductively cleave SAM to generate a 5′-deoxyadenosyl radical, which generally initiates th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204691/ https://www.ncbi.nlm.nih.gov/pubmed/35726327 http://dx.doi.org/10.1021/acsbiomedchemau.1c00059 |