Cargando…

Phenotyping Young GluA1 Deficient Mice – A Behavioral Characterization in a Genetic Loss-of-Function Model

Alterations of glutamatergic neurotransmission have been implicated in neurodevelopmental and neuropsychiatric disorders. Mice lacking the GluA1 AMPA receptor subunit, encoded by the Gria1 gene, display multiple phenotypical features associated with glutamatergic dysfunction. While the phenotype of...

Descripción completa

Detalles Bibliográficos
Autores principales: Reiber, Maria, Stirling, Helen, Sprengel, Rolf, Gass, Peter, Palme, Rupert, Potschka, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204703/
https://www.ncbi.nlm.nih.gov/pubmed/35722188
http://dx.doi.org/10.3389/fnbeh.2022.877094