Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis

Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons that synapse with tumor innervating fibers required for tumorigenesis and disease progression. Greater understanding of the mechanisms that regulate CSC driven tumor neurogenesis may therefore lead to more effectiv...

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Detalles Bibliográficos
Autores principales: Regan, Joseph L., Schumacher, Dirk, Staudte, Stephanie, Steffen, Andreas, Lesche, Ralf, Toedling, Joern, Jourdan, Thibaud, Haybaeck, Johannes, Golob-Schwarzl, Nicole, Mumberg, Dominik, Henderson, David, Győrffy, Balázs, Regenbrecht, Christian R.A., Keilholz, Ulrich, Schäfer, Reinhold, Lange, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204726/
https://www.ncbi.nlm.nih.gov/pubmed/35720265
http://dx.doi.org/10.1016/j.isci.2022.104498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204726/
https://www.ncbi.nlm.nih.gov/pubmed/35720265
http://dx.doi.org/10.1016/j.isci.2022.104498

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