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Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons that synapse with tumor innervating fibers required for tumorigenesis and disease progression. Greater understanding of the mechanisms that regulate CSC driven tumor neurogenesis may therefore lead to more effectiv...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204726/ https://www.ncbi.nlm.nih.gov/pubmed/35720265 http://dx.doi.org/10.1016/j.isci.2022.104498 |