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Confidence limits for the averted infections ratio estimated via the counterfactual placebo incidence rate

OBJECTIVES: The averted infections ratio (AIR) is a novel measure for quantifying the preservation-of-effect in active-control non-inferiority clinical trials with a time-to-event outcome. In the main formulation, the AIR requires an estimate of the counterfactual placebo incidence rate. We describe...

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Detalles Bibliográficos
Autores principales: Dunn, David T., Stirrup, Oliver T., Glidden, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204757/
https://www.ncbi.nlm.nih.gov/pubmed/35880996
http://dx.doi.org/10.1515/scid-2021-0002