Cargando…
Confidence limits for the averted infections ratio estimated via the counterfactual placebo incidence rate
OBJECTIVES: The averted infections ratio (AIR) is a novel measure for quantifying the preservation-of-effect in active-control non-inferiority clinical trials with a time-to-event outcome. In the main formulation, the AIR requires an estimate of the counterfactual placebo incidence rate. We describe...
Autores principales: | Dunn, David T., Stirrup, Oliver T., Glidden, David V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204757/ https://www.ncbi.nlm.nih.gov/pubmed/35880996 http://dx.doi.org/10.1515/scid-2021-0002 |
Ejemplares similares
-
The Connection between the Averted Infections Ratio and the Rate Ratio in Active-control Trials of Pre-exposure Prophylaxis Agents
por: Dunn, David T., et al.
Publicado: (2019) -
Interpretation of active-control randomised trials: the case for a new analytical perspective involving averted events
por: Dunn, David T., et al.
Publicado: (2023) -
Estimation of delay to diagnosis and incidence in HIV using indirect evidence of infection dates
por: Stirrup, Oliver T., et al.
Publicado: (2018) -
999. Using the F/TDF Adherence-Efficacy Relationship to Calculate Background HIV incidence: Results from the DISCOVER trial
por: Glidden, David V, et al.
Publicado: (2020) -
Using the adherence‐efficacy relationship of emtricitabine and tenofovir disoproxil fumarate to calculate background hiv incidence: a secondary analysis of a randomized, controlled trial
por: Glidden, David V, et al.
Publicado: (2021)