Inositol Hexakisphosphate (IP6) Accelerates Immature HIV-1 Gag Protein Assembly toward Kinetically Trapped Morphologies

[Image: see text] During the late stages of the HIV-1 lifecycle, immature virions are produced by the concerted activity of Gag polyproteins, primarily mediated by the capsid (CA) and spacer peptide 1 (SP1) domains, which assemble into a spherical lattice, package viral genomic RNA, and deform the p...

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Detalles Bibliográficos
Autores principales: Pak, Alexander J., Gupta, Manish, Yeager, Mark, Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204763/
https://www.ncbi.nlm.nih.gov/pubmed/35666943
http://dx.doi.org/10.1021/jacs.2c02568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204763/
https://www.ncbi.nlm.nih.gov/pubmed/35666943
http://dx.doi.org/10.1021/jacs.2c02568

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