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Inositol Hexakisphosphate (IP6) Accelerates Immature HIV-1 Gag Protein Assembly toward Kinetically Trapped Morphologies

[Image: see text] During the late stages of the HIV-1 lifecycle, immature virions are produced by the concerted activity of Gag polyproteins, primarily mediated by the capsid (CA) and spacer peptide 1 (SP1) domains, which assemble into a spherical lattice, package viral genomic RNA, and deform the p...

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Detalles Bibliográficos
Autores principales:	Pak, Alexander J., Gupta, Manish, Yeager, Mark, Voth, Gregory A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204763/ https://www.ncbi.nlm.nih.gov/pubmed/35666943 http://dx.doi.org/10.1021/jacs.2c02568

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