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A Chemical Mutagenesis Approach to Insert Post-translational Modifications in Aggregation-Prone Proteins

[Image: see text] Neurodegenerative diseases are a class of disorders linked to the formation in the nervous system of fibrillar protein aggregates called amyloids. This aggregation process is affected by a variety of post-translational modifications, whose specific mechanisms are not fully understo...

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Detalles Bibliográficos
Autores principales: Ge, Ying, Masoura, Athina, Yang, Jingzhou, Aprile, Francesco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204764/
https://www.ncbi.nlm.nih.gov/pubmed/35609278
http://dx.doi.org/10.1021/acschemneuro.2c00077