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Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants

[Image: see text] Parkinson’s Disease (PD) is characterized by the accumulation of Lewy bodies in dopaminergic neurons. The main protein component of Lewy bodies, α-synuclein (αS), is also firmly linked to PD through the identification of a number of single point mutations that are autosomal dominan...

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Detalles Bibliográficos
Autores principales: Watt, Kathryn J. C., Meade, Richard M., Williams, Robert J., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204772/
https://www.ncbi.nlm.nih.gov/pubmed/35613323
http://dx.doi.org/10.1021/acschemneuro.2c00190