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7,8-Dihydroxycoumarin Alleviates Synaptic Loss by Activated PI3K-Akt-CREB-BDNF Signaling in Alzheimer’s Disease Model Mice

[Image: see text] Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and is clinically characterized by the impairment of memory and cognition. Accumulation of β-amyloid (Aβ) in the brain is considered as a key process in the development of AD because it impairs the synapses’ funct...

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Detalles Bibliográficos
Autores principales: Yan, Li, Jin, Yufan, Pan, Junping, He, Xiang, Zhong, Shiqian, Zhang, Rongcai, Choi, LokLam, Su, Weiwei, Chen, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204815/
https://www.ncbi.nlm.nih.gov/pubmed/35657168
http://dx.doi.org/10.1021/acs.jafc.2c02140