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Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific

Dietary removal of an essential amino acid (EAA) triggers the integrated stress response (ISR) in liver. Herein, we explored the mechanisms that activate the ISR and execute changes in transcription and translation according to the missing EAA. Wild‐type mice and mice lacking general control nondere...

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Detalles Bibliográficos
Autores principales: Jonsson, William O., Mirek, Emily T., Wek, Ronald C., Anthony, Tracy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204950/
https://www.ncbi.nlm.nih.gov/pubmed/35690926
http://dx.doi.org/10.1096/fj.202200204RR