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mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination

Hippocampal CA1 parvalbumin-expressing interneurons (PV INs) play a central role in controlling principal cell activity and orchestrating network oscillations. PV INs receive excitatory inputs from CA3 Schaffer collaterals and local CA1 pyramidal cells, and they provide perisomatic inhibition. Schaf...

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Detalles Bibliográficos
Autores principales: Khlaifia, Abdessattar, Honoré, Eve, Artinian, Julien, Laplante, Isabel, Lacaille, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204956/
https://www.ncbi.nlm.nih.gov/pubmed/35715811
http://dx.doi.org/10.1186/s13041-022-00941-8