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Benchmarking imputation methods for network inference using a novel method of synthetic scRNA-seq data generation
BACKGROUND: Single cell RNA-sequencing (scRNA-seq) has very rapidly become the new workhorse of modern biology providing an unprecedented global view on cellular diversity and heterogeneity. In particular, the structure of gene-gene expression correlation contains information on the underlying gene...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204969/ https://www.ncbi.nlm.nih.gov/pubmed/35715748 http://dx.doi.org/10.1186/s12859-022-04778-9 |