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Benchmarking imputation methods for network inference using a novel method of synthetic scRNA-seq data generation

BACKGROUND: Single cell RNA-sequencing (scRNA-seq) has very rapidly become the new workhorse of modern biology providing an unprecedented global view on cellular diversity and heterogeneity. In particular, the structure of gene-gene expression correlation contains information on the underlying gene...

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Detalles Bibliográficos
Autores principales: Lasri, Ayoub, Shahrezaei, Vahid, Sturrock, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204969/
https://www.ncbi.nlm.nih.gov/pubmed/35715748
http://dx.doi.org/10.1186/s12859-022-04778-9