A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells

Patients with human papillomavirus-positive squamous cell carcinoma of the head and neck (HPV+ HNSCC) have a favorable prognosis compared to those with HPV-negative (HPV−) ones. We have shown previously that HPV+ HNSCC cell lines are characterized by enhanced radiation sensitivity and impaired DNA d...

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Detalles Bibliográficos
Autores principales: Köcher, Sabrina, Zech, Henrike Barbara, Krug, Leonie, Gatzemeier, Fruzsina, Christiansen, Sabrina, Meyer, Felix, Rietow, Ruth, Struve, Nina, Mansour, Wael Yassin, Kriegs, Malte, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Rieckmann, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204973/
https://www.ncbi.nlm.nih.gov/pubmed/35719921
http://dx.doi.org/10.3389/fonc.2022.765968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9204973/
https://www.ncbi.nlm.nih.gov/pubmed/35719921
http://dx.doi.org/10.3389/fonc.2022.765968

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