Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation

BACKGROUND: There is a lack of effective therapies for enteric nervous system (ENS) injury. Our previous study showed that transplanted bone marrow-derived mesenchymal stem cells (BMSCs) play a “glia-like cells” role in initiating ENS regeneration in denervated mice. Cellular energy metabolism is an...

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Detalles Bibliográficos
Autores principales: Fan, Mengke, Shi, Huiying, Yao, Hailing, Wang, Weijun, Zhang, Yurui, Jiang, Chen, Lin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205030/
https://www.ncbi.nlm.nih.gov/pubmed/35715822
http://dx.doi.org/10.1186/s13287-022-02936-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205030/
https://www.ncbi.nlm.nih.gov/pubmed/35715822
http://dx.doi.org/10.1186/s13287-022-02936-7

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