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Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin

BACKGROUND: Radiation-induced skin injury is a well-known risk factor for impaired wound healing. Over time, the deleterious effects of radiation on skin produce a fibrotic, hypovascular dermis poorly suited to wound healing. Despite increasing understanding of the underlying pathophysiology, therap...

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Detalles Bibliográficos
Autores principales: Lintel, Hendrik, Abbas, Darren B., Lavin, Christopher V., Griffin, Michelle, Guo, Jason L., Guardino, Nicholas, Churukian, Andrew, Gurtner, Geoffrey C., Momeni, Arash, Longaker, Michael T., Wan, Derrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205074/
https://www.ncbi.nlm.nih.gov/pubmed/35715816
http://dx.doi.org/10.1186/s12967-022-03479-4