Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury

BACKGROUND: NLRP3 inflammasome activation and pyroptosis play a significant role in myocardial ischemia reperfusion injury (MI/RI). Geniposide was reported to show potential therapeutic use for MI/RI with its anti-inflammatory and anti-oxidative properties. However, research on the specific mechanis...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Yang, Dong-Hua, Zhang, Yanmei, Zheng, Fuchun, Gao, Fenfei, Sun, Jiajia, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205109/
https://www.ncbi.nlm.nih.gov/pubmed/35715805
http://dx.doi.org/10.1186/s13020-022-00616-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205109/
https://www.ncbi.nlm.nih.gov/pubmed/35715805
http://dx.doi.org/10.1186/s13020-022-00616-5

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