Mesenchymal stem cells improve redox homeostasis and mitochondrial respiration in fibroblast cell lines with pathogenic MT-ND3 and MT-ND6 variants

The most frequent biochemical defect of inherited mitochondrial disease is isolated complex I deficiency. There is no cure for this disorder, and treatment is mainly supportive. In this study, we investigated the effects of human mesenchymal stem cells (MSCs) on skin fibroblast derived from three in...

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Detalles Bibliográficos
Autores principales: Navaratnarajah, Tharsini, Bellmann, Marlen, Seibt, Annette, Anand, Ruchika, Degistirici, Özer, Meisel, Roland, Mayatepek, Ertan, Reichert, Andreas, Baertling, Fabian, Distelmaier, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205113/
https://www.ncbi.nlm.nih.gov/pubmed/35715829
http://dx.doi.org/10.1186/s13287-022-02932-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205113/
https://www.ncbi.nlm.nih.gov/pubmed/35715829
http://dx.doi.org/10.1186/s13287-022-02932-x

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