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Effect of alendronate sodium plus vitamin D(3) tablets on knee joint structure and osteoarthritis pain: a multi-center, randomized, double-blind, placebo-controlled study protocol

BACKGROUND: Osteoarthritis (OA) is a major cause of pain and disability worldwide. Despite the relatively high burden of the disease, the currently available non-surgical treatment options are directed towards symptomatic relief. Therefore, we propose the use of alendronate as a disease modifying ag...

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Detalles Bibliográficos
Autores principales: Peng, Hui-ming, Weng, Xi-sheng, Li, Ye, Feng, Bin, Qian, Wenwei, Cai, Dao-zhang, Zhao, Chang, Yao, Zhen-jun, Yang, Yi, Zhang, Chi, Wan, Shengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205115/
https://www.ncbi.nlm.nih.gov/pubmed/35715774
http://dx.doi.org/10.1186/s12891-022-05521-4