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Effect of alendronate sodium plus vitamin D(3) tablets on knee joint structure and osteoarthritis pain: a multi-center, randomized, double-blind, placebo-controlled study protocol
BACKGROUND: Osteoarthritis (OA) is a major cause of pain and disability worldwide. Despite the relatively high burden of the disease, the currently available non-surgical treatment options are directed towards symptomatic relief. Therefore, we propose the use of alendronate as a disease modifying ag...
Autores principales: | Peng, Hui-ming, Weng, Xi-sheng, Li, Ye, Feng, Bin, Qian, Wenwei, Cai, Dao-zhang, Zhao, Chang, Yao, Zhen-jun, Yang, Yi, Zhang, Chi, Wan, Shengcheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205115/ https://www.ncbi.nlm.nih.gov/pubmed/35715774 http://dx.doi.org/10.1186/s12891-022-05521-4 |
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