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Patient-Derived Organoid Serves as a Platform for Personalized Chemotherapy in Advanced Colorectal Cancer Patients

BACKGROUND: Addition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival and served as the first line adjuvant chemotherapy in advanced colorectal cancer (CRC) patients. However, a fraction of patients remains refractory to oxaliplatin-based treatment. It is urgent t...

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Detalles Bibliográficos
Autores principales: Geevimaan, Khamushavalli, Guo, Jing-You, Shen, Chia-Ning, Jiang, Jeng-Kai, Fann, Cathy S. J., Hwang, Ming-Jing, Shui, Jr-Wen, Lin, Hsiu-Ting, Wang, Mei-Jung, Shih, Hsuan-Cheng, Li, Anna Fen-Yau, Chang, Shih-Ching, Yang, Shung-Haur, Chen, Jeou-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205170/
https://www.ncbi.nlm.nih.gov/pubmed/35719949
http://dx.doi.org/10.3389/fonc.2022.883437