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A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice

The immunoglobulin genes of inbred mouse strains that are commonly used in models of antibody-mediated human diseases are poorly characterized. This compromises data analysis. To infer the immunoglobulin genes of BALB/c mice, we used long-read SMRT sequencing to amplify VDJ-C sequences from F1 (BALB...

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Detalles Bibliográficos
Autores principales: Jackson, Katherine J. L., Kos, Justin T., Lees, William, Gibson, William S., Smith, Melissa Laird, Peres, Ayelet, Yaari, Gur, Corcoran, Martin, Busse, Christian E., Ohlin, Mats, Watson, Corey T., Collins, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205180/
https://www.ncbi.nlm.nih.gov/pubmed/35720344
http://dx.doi.org/10.3389/fimmu.2022.888555