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Human Ovarian Follicles Xenografted in Immunoisolating Capsules Survive Long Term Implantation in Mice

Female pediatric cancer survivors often develop Premature Ovarian Insufficiency (POI) owing to gonadotoxic effects of anticancer treatments. Here we investigate the use of a cell-based therapy consisting of human ovarian cortex encapsulated in a poly-ethylene glycol (PEG)-based hydrogel that replica...

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Detalles Bibliográficos
Autores principales: Brunette, Margaret A., Kinnear, Hadrian M., Hashim, Prianka H., Flanagan, Colleen L., Day, James R., Cascalho, Marilia, Padmanabhan, Vasantha, Shikanov, Ariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205207/
https://www.ncbi.nlm.nih.gov/pubmed/35721740
http://dx.doi.org/10.3389/fendo.2022.886678