Lack of ApoA-I in ApoEKO Mice Causes Skin Xanthomas, Worsening of Inflammation, and Increased Coronary Atherosclerosis in the Absence of Hyperlipidemia

BACKGROUND: HDL (high-density lipoprotein) and its major protein component, apoA-I (apolipoprotein A-I), play a unique role in cholesterol homeostasis and immunity. ApoA-I deficiency in hyperlipidemic, atheroprone mice was shown to drive cholesterol accumulation and inflammatory cell activation/prol...

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Detalles Bibliográficos
Autores principales: Busnelli, Marco, Manzini, Stefano, Colombo, Alice, Franchi, Elsa, Bonacina, Fabrizia, Chiara, Matteo, Arnaboldi, Francesca, Donetti, Elena, Ambrogi, Federico, Oleari, Roberto, Lettieri, Antonella, Horner, David, Scanziani, Eugenio, Norata, Giuseppe Danilo, Chiesa, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205301/
https://www.ncbi.nlm.nih.gov/pubmed/35587694
http://dx.doi.org/10.1161/ATVBAHA.122.317790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205301/
https://www.ncbi.nlm.nih.gov/pubmed/35587694
http://dx.doi.org/10.1161/ATVBAHA.122.317790

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