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The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes

Activin A, a TGFβ superfamily member, is important for normal testis development through its actions on Sertoli cell development. Our analyses of altered activin A mouse models indicated gonocyte abnormalities, implicating activin A as a key determinant of early germline formation. Whether it acts d...

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Detalles Bibliográficos
Autores principales: Moody, Sarah C., Whiley, Penny A. F., Western, Patrick S., Loveland, Kate L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205402/
https://www.ncbi.nlm.nih.gov/pubmed/35721752
http://dx.doi.org/10.3389/fendo.2022.896747